Browsing Dr. Norman Temple by Issue Date
Now showing items 1-20 of 61
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Investigations into the effects of cyclical rhythm and hormonal contraception on serum fat-mobilizing activity, glycerol, cholesterol and blood glucose.
(Acta Endocrinology, 1974)The effects were investigated of cyclical rhythm and hormonal contraception on serum fat-mobilizing activity, glycerol, cholesterol and whole blood glucose during 2 menstrual cycles in a group of normally menstruating young ... -
A colorimetric method for the determination of deoxyribonucleic acid in adipose tissue.
(Analyst, 1975)A method is described for measuring the deoxyribonucleic acid (DNA) content of small samples of adipose tissue or free fat cells. Lipids and acid-soluble nucleotides are first removed by extraction with a cold diethyl ... -
International Survey Data
(Trends in Biochemistry Science, 1976) -
Zonal rotor analysis of the subcellular localization of B-glycero-phosphate dehydrogenase, 1-naphthyl palmitate and 2-napthyl laurate hydrolases in the mucosa of the guinea-pig small intestine.
(Histochemistry Journal, 1976)Whole homogenate of guinea-pig small intestine mucosa was analysed by centrifugation in a zonal rotor. The results indicate that FAD-linked a-glycerophosphate dehydrogenase is localized in the mitochondria and that ... -
Zonal rotor study of the subcellular distribution of acyl-CoA synthetases, carnitine acyl transferases and phosphatidate phosphatase in the guinea-pig small intestine.
(European Journal of Cell Biology, 1979)Homogenates made from the mucosa of the guinea pig small intestine were fractionated in a zonal rotor by rate and isopycnic centrifugation in sucrose gradients. Density perturbation of endoplasmic reticulum vesicles was ... -
Intestinal peroxisomes of goldfish (Carrassius auratus) - examination for hydrolase, dehydrogenase and carnitine acetyltransferase activities.
(Comparative Biochemistry and Physiology, 1979)1. Rate sedimentation and isopycnic centrifugation were used to analyse the subcellular sites of enzymes in homogenates of goldfish intestinal mucosa. 2. The results allowed the following allocations to be made: carnitine ... -
Subcellular localization of monoglyceride acyltransferase, xanthine oxidation, NADP: isocitrate dehydrogenase and alkaline phosphatase in the mucosa of the guinea-pig small intestine.
(Comparative Biochemistry and Physiology, 1980)1. Rate dependent and isopycnic banding in a zonal rotor were used to analyse the subcellular sites of enzymes in homogenates of guinea-pig small intestinal mucosa. 2, The results demonstrate the following localizations: ... -
Strategies of subcellular fractionation suitable for analysis of peroxisomes and microperoxisomes of animal tissues.
(International Journal of Biochemistry, 1983)Strategies of subcellular fractionation are reviewed from the perspective of their utility in the analysis of peroxisomes. The considerable potential inherant in the method of rate dependent banding In zonal rotors is ... -
High fat diets and mouse colon mucosal membranes: a centrifugation study.
(Cancer Letters, 1983)Female Swiss mice were fed on a control diet (laboratory chow, 6% fat) or high fat diets (laboratory chow with added fat, principally corn oil, to produce a fat content of 16% or 23%). Homogenate of colon mucosa ... -
Refined carbohydrates - a cause of suboptimal nutrient intake.
(Medical Hypotheses, 1983)During the refining of carbohydrate foods there is a sharp drop in the concentration of dietary fiber and of various vitamins and minerals. Estimates were made of the effect of refining on the total diet intake of ... -
Coronary heart disease - dietary lipids or refined carbohydrates?
(Medical Hypotheses, 1983)The epidemiological evidence associating dietary lipids, refined carbohydrates and coronary heart disease (CHD) is evaluated. Population studies often show a high correlation between dietary lipid and heart disease ... -
High-Fat Diets and Fecal Level of Reductase and Colon Mucosal Level of Ornithine Decarboxylase, B-Glucuronidase, 5'-Nucleotidase, ATPase, and Esterase in Mice.
(Journal of the National Cancer Institute, 1984)In one experiment Swiss mice were maintained on a 16 or 23% fat diet (laboratory chow with added fat, principally corn on) or on laboratory chow alone (5.5% fat), In another experiment CS7BU1 mice were given a 23% fat ... -
Simplicity - the key to fruitful medical research
(Medical Hypotheses, 1985)Medical research is here divided -into two broad categories. The great majority of research is "complex" and includes all studies of intricate body mechanisms. A minority of research is "simple" and deals mainly ... -
Dietary fats in health
(Journal of Nutrition, Growth and Cancer, 1985)This review examines the relationship between dietary fat intake and health. ,Heal produced by modem farming methods has a high fat content in comparison with its natural counterpart and, furthermore, the fat is low in ... -
Changes in pH and levels of B-glucosidase, B-glucuronidase and reducing activity as food residue passes along the mouse colon
(Journal of Nutrition, Growth and Cancer, 1985)The contents were collected from successive regions of the colon of Swiss mice. Ana(vses show that the pH rises by about 0.55 pH units between the cecum and the distal colon. The level of p-glucuronidase falls sharply, ... -
Toxicity of 1,2-dimethlyhydrazine in mice: effect of diet and development of tolerance
(Journal of Food Safety, 1985)The effect of diet on the lethality of 1, 2-dimethylhydrazine (DMH) injections was investigated using Swiss mice. Mortality was highest when mice were fed a nutrient-dilutealfhigh-fat diet, was intermediate with a ... -
Role of selenium and cabbage in colon carcinogenesis in mice.
(Journal of the National Cancer Institute, 1987)The influence of dietary selenium and cabbage on the formation of colon tumors in female Swiss mice treated with 1,2.dimethylhydrazine [(DMH) CAS: 540-73-8] was reported. Mice received a control diet (laboratory chow), ... -
High fat and nutrient depleted diets and the metabolic profile of feces and colon mucosa of mice.
(Journal of Nutrition, Growth and Cancer, 1987)Swiss and C57BL/1 mice were fed one of the folio wing diets: commercial laboratory chow (5.5 percent fat) or chow with added starch and/or corn oil so as 10 supply a fat level of 5.5 or 23 percent, while reducing the ... -
Cabbage and vitamin E: their effect on colon tumor formation in mice.
(Cancer Letters, 1987)The effects of cabbage and vitamin E on colon carcinogenesis were investigated in Swiss mice treated with 1,2-dimethylhydrazine. Throughout the experiment the mice were fed a laboratory chow diet (46 mg vitamin E per ... -
Effect of high fat and nutrient depleted diets on colon tumor formation in mice.
(Cancer Letters, 1987)We investigated the effect of high fat and nutrient depleted diets on the formation of colon tumors in female Swiss mice treated with 1,2- dimethylhydrazine (DMH). Mice received the following diets: control diet (laboratory ...