Now showing items 21-40 of 61

    • Role of selenium and cabbage in colon carcinogenesis in mice. 

      Temple, Norman J.; Basu, Tapan K. (Journal of the National Cancer Institute, 1987)
      The influence of dietary selenium and cabbage on the formation of colon tumors in female Swiss mice treated with 1,2.dimethylhydrazine [(DMH) CAS: 540-73-8] was reported. Mice received a control diet (laboratory chow), ...
    • Effect of Dietary Beta-Carotene on Hepatic Drug-Metabolizing Enzymes in Mice 

      Basu, Tapan K. (Journal of Clinical Biochemistry and Nutrition, 1987)
      The effects of dietary supplements of beta-carotene (20-500 mg per kg diet) on hepatic microsomal drug-metabolizing enzyme activities were studied in mice. Supplementation for 14 days resulted in marked reductions in ...
    • Does Beta-Carotene Prevent Cancer? A Critical Appraisal 

      Temple, Norman J.; Basu, Tapan K. (Nutrition Research, 1988)
      The possible role of beta-carotene as a protective nutrient against cancer is reviewed. Human prospective and retrospective studies strongly indicate that beta-carotene protects against lung cancer and probably against ...
    • Dietary fibre and the mouse colon: its influence on luminal pH, reducing activity, bile acid binding and cell proliferation. 

      Temple, Norman J.; Basu, Tapan K. (Cancer Letters, 1988)
      Female, Swiss mice were fed semi-synthetic diets for 33 days. The diets were fibre-free (FF) or supplemented with corn bran (CB) 12°~, wheat bran (WB) 12%, alfalfa (AL) 12oh, pectin (P) BOh, cellulose (CL) 6%, or lignin ...
    • Pravention von Karzinomerkrankungen durch Beta-Karotin 

      Temple, Norman J.; Basu, Tapan K. (Vitamine Mineralstoffe Spurenelemente, 1988)
      Die magliche Rollevon Beta-Karotin als krebsverhiitendem Nahrungsbestandteil wird erortert. Prospektive und retrospektive Studien am Menschen deuten sehr stark daraufhin. daB Beta-Karotin eine krebsverhiitende Wirkung ...
    • Serum vitamins A and E, beta-carotene, and selenium in patients with breast cancer. 

      Basu, Tapan K.; Temple, Norman J.; Hill, Gerry B.; Ng, Dennis; Abdi, Ehtesham (Journal of the American College of Nutrition, 1989)
      A total of 89 subjects including 30 breast cancer patients' with distal metastases, 29 patients with benign breast disease, and 30 healthy subjects were studied. Serum samples from these subjects were obtained from ...
    • Evidence from immunoblotting studies that brown adipose tissue is not present in the domestic pig. 

      Trayhurn, Paul; Temple, Norman J.; Van Aerde, Johny (Canadian Journal of Physiology and Pharmacology, 1989)
      Evidence from immunoblotting studies on uncoupJing protein that brown adipose tissue is not present in the domestic pig. Can. S. Physio!. Pharmaco!. 67: 1480-1485. Adipose tissues and other tissues. of the pig have been ...
    • Biochemical status of vitamin A in colorectal cancer 

      Basu, Tapan K.; Hodgson, Anne; Temple, Norman J.; McPherson, Tony A.; Wesley, Margaret N.; Pee, David (Journal of Clinical Biochemistry and Nutrition, 1990-10)
      Serum vitamin A and its carrier proteins, retinol-binding protein and prealbumin, were measured in 41 colorectal cancer patients, 40 patients with benign colorectal disease, and 31 healthy subjects. Serum samples were ...
    • The war on cancer: failure of therapy and research 

      Temple, Norman J.; Burkitt, Denis P. (Journal of the Royal Society of Medicine, 1991)
      A generally-held beliefby both the medical profession and the lay public is that therapeutic medicine greatly affects health. Providing more hospital beds, doctors and resources is viewed as the path to improve ...
    • Towards a new system of health: the challenge of western disease 

      Temple, Norman J.; Burkitt, Denis P. (Journal of Community Health, 1993)
      Over the last three decades, the concept of Western disease has become well established. Medicine has approached this group of diseases by searching for new cures but has achieved relatively little success. We argue ...
    • Tribute to Denis Burkitt 

      Nelson, Cliff L.; Temple, Norman J. (Journal of Medical Biography, 1994)
    • Diet, blood lipids and coronary heart disease: current controversies 

      Temple, Norman J. (South African Medical Journal, 1994)
    • Blood cholesterol and coronary heart disease: changing perspectives 

      Temple, Norman J.; Walker, Alexander R.P. (Journal of the Royal Society of Medicine, 1994)
      There has been much controversy concerning the value of efforts to reduce blood cholesterol levels. In this contribution, the risks and benefits of interventions are discussed. Lowering cholesterol level by drugs is ...
    • Dietary fats and coronary heart disease. 

      Temple, Norman J. (Biomedicine Pharmacotherapy, 1996)
      The prevention and treatment of coronary heart disease (CHD) necessitates vigorous dietary intervention so as 10 lower the serum cho1eslero11evel by at least 6%. Greater decreases in serum cholesterol can bring about ...
    • Survey of nutrition knowledge of Canadian physicians 

      Temple, Norman J. (Journal of the American College of Nutrition, 1999)
      Objectives: Previous reports have indicated that physicians generally have little training in nutrition and a poor knowledge of the subject. A survey was carried out to determine the nutrition knowledge of physicians working ...
    • Fruit, vegetables, and cancer prevention trials 

      Temple, Norman J. (Journal of the National Cancer Institute, 1999)
    • Survey of nutrition knowledge of Canadian physicians 

      Temple, Norman J. (Journal of the American College of Nutrition, 1999)
      Objectives: Previous reports have indicated that physicians generally have little training in nutrition and a poor knowledge of the subject. A survey was carried out to determine the nutrition knowledge of physicians working ...
    • Antioxidants and disease: more questions than answers 

      Temple, Norman J. (Nutrition Research, 2000)
      Reactive oxygen species are widely believed to be involved in the etiology of many diseases as indicated by the signs of oxidative stress seen in those diseases. Conversely, antioxidants are believed to be protective. ...
    • Dietary flavonoid intake and risk of cardiovascular disease. American 

      Temple, Norman J. (American Journal of Epidemiology, 2000)
    • The epidemic of obesity in South Africa: a study in a disadvantaged community. 

      Temple, Norman J.; Steyn, Krisela; Hoffman, Margaret; Levitt, Naomi S.; Lombard, Carl J. (Ethnicity Disease, 2001)
      Objective: The objective of this study was: 1) to determine the anthropometric profile of adults In Mamre, a small town In South Africa, which has a population of mixed ancestry ("colored" people of Afro-Euro-Malay-Khoisan ...


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