Browsing by Author "Carrero, Gustavo"
Now showing items 1-4 of 4
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A Diffusion-approximation Approach to Model Self-organization of Nuclear Proteins
Carrero, Gustavo (2009-06-29)The existence of domains within the cell nucleus enriched in specific proteins capable of moving randomly throughout the nucleoplasm has led to the biological conclusion that the cell nucleus is dynamically and highly ... -
Studying receptor diffusion by interpreting SPT data with a correlated random walk and a first-passage time algorithm
Carrero, Gustavo (2010-09-21)One of the most powerful and commonly used methods for studying molecular diffusion on the cell membrane is Single Particle Tracking (SPT). During an SPT experiment, the trajectory of a membrane-associated biomolecule, ... -
Understanding Histone H1 Binding Mechanism Through Model Comparison and FRAP Experiments
Carrero, Gustavo (2011-08-25)Histone H1 or linker histones play an important role in the package and order of DNA in eukaryotic cell nuclei by associating to and dissociating from the chromatin structure. Thus, in order to better understand the formation ... -
Using mathematical modelling to understand the role the linker histone dynamics in DNA packaging
Carrero, Gustavo (2013-03-05)Nuclear proteins responsible for DNA packaging during the interphase of the cell cycle are highly mobile and their dynamics have a strong influence in the organization of the chromatic structure (DNA and associated proteins). ...